bioRxiv

bioRxiv is a non-profit preprint server for the biological sciences, operated by Cold Spring Harbor Laboratory. Since its inception, it has revolutionized scientific communication by allowing researchers to share findings immediately before formal peer review. Architecturally, bioRxiv utilizes the HighWire Press platform, offering robust versioning and persistent identification through Digital Object Identifiers (DOIs). By 2026, bioRxiv has solidified its position as the critical infrastructure for the global 'Open Science' movement, integrating advanced AI screening tools to detect image manipulation and plagiarism at the submission stage. Its technical stack supports complex metadata harvesting via the bioRxiv API, enabling large-scale data mining for pharmaceutical R&D and academic meta-analyses. The platform facilitates a 'decoupled' publishing model where community feedback and automated technical checks occur in parallel with traditional journal submission, significantly reducing the 'time-to-knowledge' gap in critical fields like genomics and epidemiology.