Limbix (by BigHealth)
Evidence-based digital therapeutics for adolescent mental health and behavioral activation.
The non-invasive gold standard for coronary artery disease diagnosis using AI and fluid dynamics.
HeartFlow is a leader in precision heart care, utilizing a proprietary AI-powered platform to transform standard Coronary Computed Tomography Angiography (CCTA) scans into personalized 3D models of the heart's arteries. The core technology, the HeartFlow FFRct Analysis, applies advanced Computational Fluid Dynamics (CFD) and deep learning algorithms to simulate blood flow and calculate Fractional Flow Reserve (FFR) values non-invasively. By 2026, HeartFlow has expanded its suite to include comprehensive Plaque Analysis and RoadMap vessel guidance, positioning itself as the central intelligence layer for 'CT-first' cardiac care strategies. The architecture operates on a secure cloud-based model where DICOM data is uploaded, processed by AI models trained on millions of data points, and validated by expert analysts. This process effectively reduces the rate of unnecessary invasive coronary angiograms by providing clinicians with both anatomical and functional insights into coronary artery disease (CAD). The platform is deeply integrated into hospital PACS systems and complies with global medical standards, including FDA 510(k) clearances and CE marking, ensuring high-fidelity diagnostic accuracy for complex clinical decision-making.
Uses computational fluid dynamics to calculate pressure drops across stenoses without invasive wires.
Evidence-based digital therapeutics for adolescent mental health and behavioral activation.
Predictive clinical and operational intelligence to fight death and waste in healthcare.
Predictive medical data and clinical insights for streamlined enterprise underwriting.
The professional medical network for clinicians, providing HIPAA-compliant AI and telehealth solutions.
Verified feedback from the global deployment network.
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Automated quantification and characterization of calcified and non-calcified plaque volumes.
AI-driven color-coded guidance overlaying the entire coronary tree to identify narrowing.
Neural networks trained on over 20 million images for precise anatomical lumen tracking.
Scalable GPU-accelerated infrastructure for complex fluid simulation processing.
Web-based interface allowing clinicians to rotate and inspect vessels in 3D space.
Automated delivery of structured diagnostic data into Epic or Cerner platforms.
Reducing unnecessary invasive coronary angiographies (ICA) in patients with inconclusive stress tests.
Registry Updated:2/7/2026
Identifying optimal targets for bypass grafting using functional vessel data.
Determining if a side-branch lesion is causing significant flow restriction.