Integrative Genomics Viewer (IGV)

The Integrative Genomics Viewer (IGV) is a high-performance, interactive visualization tool designed for the exploration of large-scale, integrated genomic datasets. Developed by the Broad Institute of MIT and Harvard, it supports a wide variety of data types, including next-generation sequencing (NGS) data, genomic annotations, and clinical information. As of 2026, IGV remains the gold standard in the bioinformatics field for visual verification of sequencing results, bridging the gap between automated pipelines and biological interpretation. Its architecture is built to handle massive datasets efficiently through the use of indexed file formats (BAM, CRAM, VCF, BigWig), which allow for rapid zooming and panning across the entire genome. IGV is available in three primary distributions: the feature-rich Desktop application, the light-weight IGV-Web, and the igv.js embeddable library for web developers. It excels in integrating data from multiple sources, including local files, cloud storage like Google Cloud and Amazon S3, and public data repositories like ENCODE and the 1000 Genomes Project. Its robust support for multi-omics integration and structural variant visualization makes it indispensable for researchers and clinical labs globally.