Who should use the Infectious Disease Diagnostics with Biotia workflow?
Teams or solo builders working on healthcare tasks who want a repeatable process instead of one-off tool experiments.
AI Workflow · Healthcare
End-to-end workflow for rapid and accurate infectious disease diagnostics using Biotia's AI-powered metagenomics platform, from sample submission to clinical report generation.
Deliverable outcome
Data preserved for audit, research, or public health reporting.
30-90 minutes
Includes setup plus initial result generation
Free to start
You can swap tools by pricing and policy requirements
Data preserved for audit, research, or public health reporting.
Use each step output as the input for the next stage
Step map
Instead of relying on a single generic AI model, this pipeline connects specialized tools to maximize quality. First, you'll use Biotia to sample is properly collected, labeled, and linked to clinical context in the system. Then, you pass the output to Biotia to high-quality, barcoded library ready for sequencing with minimal host background. Then, you pass the output to Biotia to raw sequencing data (fastq files) generated with >80% bases above q30. Then, you pass the output to Biotia to list of identified pathogens (species level) with associated amr gene profiles and confidence scores. Then, you pass the output to Biotia to clinically actionable report delivered to the healthcare provider within 24-48 hours of sample receipt. Finally, Biotia is used to data preserved for audit, research, or public health reporting.
Sample Collection and Metadata Entry
Sample is properly collected, labeled, and linked to clinical context in the system.
Nucleic Acid Extraction and Library Preparation
High-quality, barcoded library ready for sequencing with minimal host background.
Next-Generation Sequencing (NGS) Run
Raw sequencing data (FASTQ files) generated with >80% bases above Q30.
AI-Powered Pathogen Identification and Antimicrobial Resistance (AMR) Profiling
List of identified pathogens (species level) with associated AMR gene profiles and confidence scores.
Clinical Interpretation and Report Generation
Clinically actionable report delivered to the healthcare provider within 24-48 hours of sample receipt.
Data Archival and Optional Secondary Analysis
Data preserved for audit, research, or public health reporting.
Collect the clinical specimen (e.g., blood, CSF, or tissue) using sterile techniques and immediately log it into Biotia's platform. Enter relevant patient metadata (symptoms, travel history, comorbidities) to contextualize the analysis.
Why Biotia: Biotia provides the sample submission portal and is directly designed for infectious disease diagnostics from metagenomic data, matching the step's needs.
Extract total nucleic acids (DNA/RNA) from the sample using a validated extraction kit, then prepare a metagenomic NGS library with adapter ligation and amplification. Include a negative control to monitor contamination.
Why Biotia: Biotia is the only tool in the menu that aligns with metagenomic sequencing workflows, which includes nucleic acid extraction and library preparation for infectious disease diagnostics.
Load the pooled library onto a sequencing platform (e.g., Illumina NextSeq or Nanopore) and run for sufficient depth (≥5 million reads per sample). Monitor run metrics for quality (Q30 scores, cluster density).
Why Biotia: Biotia is designed for metagenomic sequencing data analysis, which directly supports the NGS run step in infectious disease diagnostics.
Upload FASTQ files to Biotia's cloud platform, which uses machine learning to filter human reads, classify microbial taxa, and detect AMR genes. Review the automated report for top pathogen candidates and resistance markers.
Why Biotia: Biotia specifically performs AI-powered pathogen identification and antimicrobial resistance profiling from metagenomic sequencing data, exactly matching this step.
Interpret the AI results in the context of patient metadata and clinical guidelines. Generate a final diagnostic report that includes pathogen identity, AMR profile, and treatment recommendations (e.g., antibiotics).
Why Biotia: Biotia provides clinical interpretation and report generation for infectious disease diagnostics, including EHR integration and clinical decision support.
Archive raw sequencing data and reports in a secure repository for future reference or outbreak tracking. Optionally, perform phylogenetic analysis or longitudinal comparison if the case is part of a surveillance study.
Why Biotia: Biotia includes an archival module and supports optional secondary analysis like phylogenetic analysis for outbreak surveillance.
§ Before you start
Teams or solo builders working on healthcare tasks who want a repeatable process instead of one-off tool experiments.
No. Start with the top pick for each step, then replace tools only if they do not fit your pricing, compliance, or output needs.
Open the mapped task page and compare top options side by side. Prioritize output quality, integration fit, and predictable cost before scaling.
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